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11.
Meccanica - The advancement of manufacturing techniques has led to a rapid increase in the design and fabrication of periodic and architectured materials for a variety of dynamics and wave... 相似文献
12.
13.
Russian Chemical Bulletin - Oxidation of methane with a hydrogen-air mixture at 70 °C and a partial pressure of methane of 30 atm was studied. Water-soluble glutathione-stabilized nanoclusters... 相似文献
14.
Ultrasound has been recognized as an exciting tool to enhance the therapeutic efficacy in tumor chemotherapy owing to the triggered drug release, facilitated intracellular drug delivery, and improved spatial precision. Aiming for a precise localized drug delivery, novel dendritic polyurethane-based prodrug (DOX-DPU-PEG) was fabricated with a drug content of 18.9% here by conjugating DOX onto the end groups of the functionalized dendritic polyurethane via acid-labile imine bonds. It could easily form unimolecular micelles around 38 nm. Compared with the non-covalently drug-loaded unimolecular micelles (DOX@Ph-DPU-PEG), they showed excellent pH/ultrasound dual-triggered drug release performance, with drug leakage of only 4% at pH 7.4, but cumulative release of 14% and 88% at pH 5.0 without and with ultrasound, respectively. The ultrasound responsiveness was attributed to the unique strawberry-shaped topological structure of the DOX-DPU-PEG, in which DOX was embedded in the skin layer of the hydrophobic DPU cores. With ultrasound, the DOX-DPU-PEG unimolecular micelles possessed enhanced tumor growth inhibition than free DOX but showed no obvious cytotoxicity on the tumor cells without ultrasound. Such feature makes them promising potential for precise localized drug delivery. 相似文献
15.
Chumaevskii A. V. Zykova A. P. Gusarova A. V. Guryanov D. A. Rubtsov V. E. Kolubaev E. A. 《Russian Physics Journal》2022,65(2):303-311
Russian Physics Journal - The results of model experimental studies of structural-phase changes in an AA2024 aluminum alloy after friction with a counter-body of a complex configuration are... 相似文献
16.
Timofeev V. I. Abramchik Yu. A. Muravyova T. I. Zhukhlistova N. E. Esipov R. S. Kuranova I. P. 《Crystallography Reports》2021,66(5):769-776
Crystallography Reports - The three-dimensional structure of recombinant thermophilic ribokinase from Thermus speсies 2.9 was determined at 2.4 Å resolution using crystals, which were... 相似文献
17.
Guzev M. A. Liu W. Qi Ch. Riabokon E. P. 《Journal of Applied Mechanics and Technical Physics》2021,62(5):736-741
Journal of Applied Mechanics and Technical Physics - A self-equilibrated stress field for an incompressible sphere is constructed based on a non-Euclidean continuum model. The... 相似文献
18.
Butenko A. V. Galimov A. R. Meshkov I. N. Syresin E. M. Tolstikhina I. Yu. Tuzikov A. V. Philippov A. V. Khodzhibagiyan H. G. Shevel’ko V. P. 《JETP Letters》2021,113(12):752-756
JETP Letters - The results of the first run (December 2020) for the commissioning of the new superconducting synchrotron Booster at the Joint Institute for Nuclear Research are presented. Vacuum... 相似文献
19.
Optics and Spectroscopy - We consider the features of the dimensional transformation of images of depth-extended objects, which are reconstructed by transmission pulse holograms, with differences... 相似文献
20.
Bryzgunov M. I. Denisov A. P. Panasyuk V. M. Parkhomchuk V. V. Reva V. B. Chekavinskii V. A. 《Technical Physics》2021,66(5):716-723
Technical Physics - A high-voltage system for electron cooling of the COSY (Germany) synchrotron is featured by the presence of a profile monitor that is used for measurement of current density... 相似文献